Naloxone is a prescription medication that reverses opioid overdoses. Naloxone has been used by medical professionals since 1971. It is NOT a controlled substance, NOT addictive, and DOES NOT enable people who use drugs to use more drugs. It is LIFE-SAVING medication in the event of an opioid overdose. Similarly to people who need an EpiPen during an anaphylactic reaction. Naloxone reverses only opioid overdoses, and it does not cause harm to people who are not in an opioid overdose. It comes in several different formulations, the most common being intranasal or intramuscular.